冬虫夏草固体发酵物水提液抗疲劳作用初步研究Anti-fatigue Activity of Hot Aqueous Extracts of Ophiocordyceps sinensis Mycelium Evaluated Using a Mouse Model
【作者】 闫文娟; 李泰辉; 劳景辉; 沈亚恒; 方佳茂;
【Author】 YAN Wenjuan1,LI Taihui1,LAO Jinghui1,SHEN Yaheng 1,FANG Jiamao2(1Guangdong Institute of Microbiology,Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application,Guangdong Open Laboratory of Applied Microbiology,State Key Laboratory of Applied Microbiology (Ministry-Guangdong Province Jointly Breeding Base),South China,Guangzhou,Guangdong 510070,China;2Huanxi Biological Technology Co.,Ltd,Puning,Guangdong 515343,China)
【机构】 广东省微生物研究所,广东省菌种保藏与应用重点实验室,广东省微生物应用新技术公共实验室,广东省华南应用微生物重点实验室—省部共建国家重点实验室培育基地; 广东环西生物科技股份有限公司;
【摘要】 通过研究冬虫夏草(Ophiocordyceps sinensis)固体发酵物水提液对负重小鼠游泳时间的影响,初步探讨其抗疲劳作用。结果表明:与阴性对照组相比,灌胃喂养冬虫夏草固体发酵物水提液的小鼠负重游泳时间显著延长,证明在本试验条件下冬虫夏草固体发酵物具有显著的抗疲劳作用。
【Abstract】 Ophiocordyceps sinensis mycelium was grown in 250 mL glass bottles on a solid medium consisting of 1% glucose,0.5% peptone,0.3% yeast extract and 0.3% malt extract in distilled water mixed with rice(1.5∶1).Hot(80-99 ℃) aqueous extracts of fungal mycelium grown for 25-30 d were administered to mice as part of their daily liquid intake(0.2 mL/10 g body weight) for 30 d and the anti-fatigue effects were evaluated using the weight-loaded swimming times of the mice as indicator.Extracts at a dose lev...
【关键词】 冬虫夏草; 小鼠; 抗疲劳;
【Key words】 Ophiocordyceps sinensis; hot aqueous extracts; anti-fatigue effects in mice;
【基金】 广东省基金项目(编号:10151007002000006);广东省科技计划项目(编号:2009B080702029、2010A030100015);广东省产学研项目(编号:2011B090400625)的部分研究内容
【分类号】R285.5